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1

ChemInform Abstract: Magnesium Coordination-Directed N-Selective Stereospecific Alkylation of 2-Pyridones, Carbamates, and Amides Using α-Halocarboxylic Acids.

Yuan-Qing Fang, Matthew M. Bio, Karl B. Hansen, Matthew S. Potter, Andrew Clausen

Journal:

Année:

2011

Fichier:

PDF, 45 KB

2011

2

Magnesium Coordination-Directed N -Selective Stereospecific Alkylation of 2-Pyridones, Carbamates, and Amides Using α-Halocarboxylic Acids

Fang, Yuan-Qing, Bio, Matthew M., Hansen, Karl B., Potter, Matthew S., Clausen, Andrew

Journal:

Journal of the American Chemical Society

Année:

2010

Langue:

english

Fichier:

PDF, 361 KB

english, 2010

3

Stereoconvergent Palladium-Catalyzed Carbonylation of Both E and Z Isomers of a 2-Trifloxy-1,3-butadiene

Bio, Matthew M., Leighton, James L.

Journal:

Organic Letters

Année:

2000

Langue:

english

Fichier:

PDF, 57 KB

english, 2000

4

Highly Regioselective Halogenation of Pyridine N -Oxide: Practical Access to 2-Halo-Substituted Pyridines

Chen, Ying, Huang, Jinkun, Hwang, Tsang-Lin, Chen, Maosheng J., Tedrow, Jason S., Farrell, Robert P., Bio, Matthew M., Cui, Sheng

Journal:

Organic Letters

Année:

2015

Langue:

english

Fichier:

PDF, 703 KB

english, 2015

5

Crystallization-Induced Dynamic Resolution of a Diarylmethylamine toward the Synthesis of a Potent TRPM8 Inhibitor

Beaver, Matthew G., Langille, Neil F., Cui, Sheng, Fang, Yuan-Qing, Bio, Matthew M., Potter-Racine, Matthew S., Tan, Helming, Hansen, Karl B.

Journal:

Organic Process Research & Development

Année:

2016

Langue:

english

Fichier:

PDF, 920 KB

english, 2016

6

A Scalable Membrane Pervaporation Approach for Continuous Flow Olefin Metathesis

Breen, Christopher P., Parrish, Christine, Shangguan, Ning, Majumdar, Sudip, Murnen, Hannah, Jamison, Timothy F., Bio, Matthew M.

Journal:

Organic Process Research & Development

Année:

2020

Fichier:

PDF, 1.18 MB

2020

7

Continuous Process for Preparing the Difluoromethylating Reagent [(DMPU) 2 Zn(CF 2 H) 2 ] and Improved Synthesis of the ICHF 2 Precursor

Monfette, Sebastien, Fang, Yuan-Qing, Bio, Matthew M., Brown, Adam R., Crouch, Ian T., Desrosiers, Jean-Nicolas, Duan, Shengquan, Hawkins, Joel M., Hayward, Cheryl M., Peperni, Nikita, Rainville, Jose

Journal:

Organic Process Research & Development

Année:

2020

Fichier:

PDF, 792 KB

2020

8

The Innate Immune Response of Atlantic Salmon (Salmo salar) Is Not Negatively Affected by High Temperature and Moderate Hypoxia

Zanuzzo, FÃ¡bio S., Beemelmanns, Anne, Hall, Jennifer R., Rise, Matthew L., Gamperl, Anthony K.

Journal:

Frontiers in Immunology

Année:

2020

Fichier:

PDF, 1.59 MB

2020

9

Practical Synthesis of a Potent Hepatitis C Virus RNA Replication Inhibitor.

Matthew M. Bio, Feng Xu, et al. et al.

Journal:

Année:

2005

Fichier:

PDF, 8 KB

2005

10

An Improved Synthesis of N-Isocyanoiminotriphenylphosphorane and Its Use in the Preparation of Diazoketones.

Matthew M. Bio, Gary Javadi, Zhiguo Jake Song

Journal:

Année:

2005

Fichier:

PDF, 18 KB

2005

11

ChemInform Abstract: Regioselective Coupling Reactions of 2,4-Diaminopyridine Derivatives with Aryl Halides: The Synthesis of Elaborated Pyridines.

Matthew M. Bio, Ed Cleator, Antony J. Davies, Simon E. Hamilton, Andrew Lawrence, Faye J. Sheen, Gavin W. Stewart, Robert D. Wilson

Journal:

Année:

2010

Fichier:

PDF, 43 KB

2010

12

Regioselective coupling reactions of 2,4-diaminopyridine derivatives with aryl halides: the synthesis of elaborated pyridines

Matthew M. Bio, Ed Cleator, Antony J. Davies, Simon E. Hamilton, Andrew Lawrence, Faye J. Sheen, Gavin W. Stewart, Robert D. Wilson

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 434 KB

english, 2009

13

Enantioselective hydrogenation of an α-alkoxy substituted ketone with chiral ruthenium (phosphinoferrocenyl)oxazoline complexes

David M. Tellers, Matthew Bio, Zhiguo J. Song, J. Christopher McWilliams, Yongkui Sun

Journal:

Tetrahedron: Asymmetry

Année:

2006

Langue:

english

Fichier:

PDF, 115 KB

english, 2006

14

Regioselective synthesis of N-substituted-4-substituted isothiazolidine-1,1-dioxides

Ed Cleator, Faye J. Sheen, Matthew M. Bio, K.M. Jos Brands, Antony J. Davies, Ulf-H. Dolling

Journal:

Tetrahedron Letters

Année:

2006

Langue:

english

Fichier:

PDF, 99 KB

english, 2006

15

Selective protodeboronation: synthesis of 4-methyl-2-thiopheneboronic anhydride and demonstration of its utility in Suzuki–Miyaura reactions

Liane M. Klingensmith, Matthew M. Bio, George A. Moniz

Journal:

Tetrahedron Letters

Année:

2007

Langue:

english

Fichier:

PDF, 115 KB

english, 2007

16

Development of a Scaleable Synthesis of a Partial Nicotinic Acid Receptor Agonist

Wilson, Robert D., Cleator, Ed, Ashwood, Michael S., Bio, Matthew M., Brands, Karel M. J., Davies, Antony J., Dolling, Ulf-H., Emerson, Khateeta M., Gibb, Andrew D., Hands, David

Journal:

Organic Process Research & Development

Année:

2009

Langue:

english

Fichier:

PDF, 497 KB

english, 2009

17

A Practical, Efficient Synthesis of 1,1-Dioxo-hexahydro-1λ6-thiopyran-4-carbaldehyde

Bio, Matthew M., Hansen, Karl B., Gipson, John

Journal:

Organic Process Research & Development

Année:

2008

Langue:

english

Fichier:

PDF, 110 KB

english, 2008

18

A highly regioselective Friedländer reaction mediated by lanthanum chloride

Ying Chen, Jinkun Huang, Tsang-Lin Hwang, T.J. Li, Sheng Cui, Johann Chan, Matthew Bio

Journal:

Tetrahedron Letters

Année:

2012

Langue:

english

Fichier:

PDF, 4.47 MB

english, 2012

19

Practical Access to Metallo Thiophenes: Regioselective Synthesis of 2,4-Disubstituted Thiophenes

Bio, Matthew M., Langille, Neil F., Ngai, Ka Yi, Asselin, Sylvie M.

Journal:

Organic Process Research & Development

Année:

2010

Langue:

english

Fichier:

PDF, 418 KB

english, 2010

20

ChemInform Abstract: A Highly Regioselective Friedlaender Reaction Mediated by Lanthanum Chloride.

Ying Chen, Jinkun Huang, Tsang-Lin Hwang, T. J. Li, Sheng Cui, Johann Chan, Matthew Bio

Journal:

Année:

2012

Fichier:

PDF, 29 KB

2012

21

Practical Synthesis of a Potent Hepatitis C Virus RNA Replication Inhibitor

Bio, Matthew M., Xu, Feng, Waters, Marjorie, Williams, J. Michael, Savary, Kimberly A., Cowden, Cameron J., Yang, Chunhua, Buck, Elizabeth, Song, Zhiguo J., Tschaen, David M., Volante, R. P., Reamer,

Journal:

Journal of Organic Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 200 KB

english, 2004

22

Practical Syntheses of a CXCR3 Antagonist

Chan, Johann, Burke, Brenda J., Baucom, Kyle, Hansen, Karl, Bio, Matthew M., DiVirgilio, Evan, Faul, Margaret, Murry, Jerry

Journal:

Journal of Organic Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 1.17 MB

english, 2011

23

Process Development and Multikilogram-Scale Synthesis of a TRPV1 Antagonist

Cleator, Ed, Scott, Jeremy P., Avalle, Paulo, Bio, Matthew M., Brewer, Sarah E., Davies, Antony J., Gibb, Andrew D., Sheen, Faye J., Stewart, Gavin W., Wallace, Debra J., Wilson., Robert D.

Journal:

Organic Process Research & Development

Année:

2013

Langue:

english

Fichier:

PDF, 370 KB

english, 2013

24

An Approach to the Synthesis of the Phomoidrides

Bio, Matthew M., Leighton, James L.

Journal:

Journal of Organic Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 249 KB

english, 2003

25

An Approach to the Synthesis of CP-263,114: A Remarkably Facile Silyloxy-Cope Rearrangement

Bio, Matthew M., Leighton, James L.

Journal:

Journal of the American Chemical Society

Année:

1999

Langue:

english

Fichier:

PDF, 73 KB

english, 1999

26

A Practical and Scaleable Synthesis of 1 R ,5 S -Bicyclo[3.1.0]hexan-2-one: The Development of a Catalytic Lithium 2,2,6,6-Tetramethylpiperidide (LTMP) Mediated Intramolecular Cyclopropanation of ( R )-1,2-Epoxyhex-5-ene

Alorati, Anthony D., Bio, Matthew M., Brands, Karel M. J., Cleator, Ed, Davies, Antony J., Wilson, Robert D., Wise, Chris S.

Journal:

Organic Process Research & Development

Année:

2007

Langue:

english

Fichier:

PDF, 57 KB

english, 2007

27

Some Practical Methods for the Application of 5-Metallo-1-benzyl-1H-tetrazoles in Synthesis

Wiedemann, Sean, Bio, Matthew, Brown, Liane, Hansen, Karl, Langille, Neil

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 274 KB

english, 2012

28

Synthesis of 4-Substituted Phthalazin-1(2 H )-ones from 2-Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate through PAT-Guided Process Development

Mennen, Steven M., Mak-Jurkauskas, Melody L., Bio, Matthew M., Hollis, L. Steven, Nadeau, Kelly A., Clausen, Andrew M., Hansen, Karl B.

Journal:

Organic Process Research & Development

Année:

2015

Langue:

english

Fichier:

PDF, 2.50 MB

english, 2015

29

An Efficient Synthesis of an NMDA Receptor Antagonist via Stereoselective Fluorination

Bio, Matthew, Waters, Marjorie, Javadi, Gary, Song, Zhiguo, Zhang, Fei, Thomas, Dave

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 128 KB

english, 2008

30

Telescoped Process to Manufacture 6,6,6-Trifluorofucose via Diastereoselective Transfer Hydrogenation: Scalable Access to an Inhibitor of Fucosylation Utilized in Monoclonal Antibody Production

Achmatowicz, Michal M., Allen, John G., Bio, Matthew M., Bartberger, Michael D., Borths, Christopher J., Colyer, John T., Crockett, Richard D., Hwang, Tsang-Lin, Koek, Jan. N., Osgood, Stephen A., Rob

Journal:

Journal of Organic Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 980 KB

english, 2016

31

ChemInform Abstract: Synthesis of 4-Substituted Phthalazin-1(2H)-ones from 2-Acylbenzoic Acids: Controlling Hydrazine in a Pharmaceutical Intermediate Through PAT-Guided Process Development.

Mennen, Steven M., Mak-Jurkauskas, Melody L., Bio, Matthew M., Hollis, L. Steven, Nadeau, Kelly A., Clausen, Andrew M., Hansen, Karl B.

Journal:

Année:

2015

Fichier:

PDF, 18 KB

2015

32

ChemInform Abstract: Rh(III)-Catalyzed C-H Activation and Double Directing Group Strategy for the Synthesis of Naphthyridinones.

Huckins, John R., Becot, Eric A., Thiel, Oliver R., Hwang, Tsang-Lin, Bio, Matthew M.

Journal:

Année:

2014

Fichier:

PDF, 35 KB

2014

33

ChemInform Abstract: Highly Regioselective Halogenation of Pyridine N-Oxide: Practical Access to 2-Halo-Substituted Pyridines.

Chen, Ying, Huang, Jinkun, Hwang, Tsang-Lin, Chen, Maosheng J., Tedrow, Jason S., Farrell, Robert P., Bio, Matthew M., Cui, Sheng

Journal:

Année:

2015

Fichier:

PDF, 23 KB

2015

34

Flow Asymmetric Propargylation: Development of Continuous Processes for a Chiral beta-Amino Alcohol

Fang, Yuan-Qing, Li, Hui, Sheeran, Jillian W, Clausen, Andrew M, Bio, Matthew M, Bader, Scott

Journal:

Angewandte Chemie International Edition

Année:

2017

Langue:

english

Fichier:

PDF, 1.21 MB

english, 2017

35

Flow Asymmetric Propargylation: Development of Continuous Processes for the Preparation of a Chiral β-Amino Alcohol

Li, Hui, Sheeran, Jillian W., Clausen, Andrew M., Fang, Yuan-Qing, Bio, Matthew M., Bader, Scott

Journal:

Angewandte Chemie

Année:

2017

Langue:

english

Fichier:

PDF, 1.45 MB

english, 2017

36

Ni-Catalyzed Electrochemical Decarboxylative C–C Couplings in Batch and Continuous Flow

Li, Hui, Breen, Christopher P., Seo, Hyowon, Jamison, Timothy F., Fang, Yuan-Qing, Bio, Matthew M.

Journal:

Organic Letters

Année:

2018

Langue:

english

Fichier:

PDF, 1.06 MB

english, 2018

37

Predictors of Antimicrobial Stewardship Program Recommendation Disagreement

Bio, Laura L., Kruger, Jenna F., Lee, Betty P., Wood, Matthew S., Schwenk, Hayden T.

Journal:

Infection Control and Hospital Epidemiology

Année:

2018

Langue:

english

Fichier:

PDF, 848 KB

english, 2018

38

Development of a Robust and Highly-Selective Ru(II)-Catalyzed Dynamic Kinetic Resolution Used to Manufacture AMG 232

Smith, Austin Gerald, Bio, Matthew Michael, Colyer, John T, DIKER, Khalid, Gorins, Gilles, Jones, Sian, Silva Elipe, Maria V., Tedrow, Jason S., Walker, Shawn D., Caille, Seb

Journal:

Organic Process Research & Development

Année:

2020

Langue:

english

Fichier:

PDF, 642 KB

english, 2020

39

1136. Antifungal Prescribing Patterns among Hospitalized Children in the United States: Are There Opportunities for Antifungal Stewardship?

Eguiguren, Lourdes, Bio, Laura, Lee, Brian R, Newland, Jason, Hersh, Adam, Gerber, Jeffrey, Kronman, Matthew, Lee, Grace, Schwenk, Hayden

Journal:

Open Forum Infectious Diseases

Année:

2019

Fichier:

PDF, 328 KB

2019

40

CAFE 5 models variation in evolutionary rates among gene families

Mendes, FÃ¡bio K, Vanderpool, Dan, Fulton, Ben, Hahn, Matthew W, Robinson, Peter

Journal:

Année:

2020

Fichier:

PDF, 249 KB

2020